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CG5776 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34680, updated on 9-Dec-2024

Summary

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Official Symbol
CG5776provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032450
Locus tag
Dmel_CG5776
See related
AllianceGenome:FB:FBgn0032450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5776
Summary
Predicted to enable ATP hydrolysis activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be active in cytoplasm. Is expressed in organism. Orthologous to human AFG2A (AFG2 AAA ATPase homolog A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG5776 in Genome Data Viewer
Location:
33F3-33F3; 2-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12700949..12704451, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12700949..12704451, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Protein interacting with C kinase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene spichthyin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic screening for modifiers of the DREF pathway in Drosophila melanogaster: identification and characterization of HP6 as a novel target of DREF. Ida H, et al. Nucleic Acids Res, 2009 Apr. PMID 19136464, Free PMC Article
  2. ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD. Park J, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34551427, Free PMC Article
  3. Identification and Characterization of Breakpoints and Mutations on Drosophila melanogaster Balancer Chromosomes. Miller DE, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972999, Free PMC Article
  4. Phenotypes Associated with Second Chromosome P Element Insertions in Drosophila melanogaster. Kahsai L, et al. G3 (Bethesda), 2016 Aug 9. PMID 27317776, Free PMC Article
  5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5776-PA
CG5776-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    12700949..12704451 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273491.2 → NP_001260420.1  uncharacterized protein Dmel_CG5776, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260420.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VK63
    Conserved Domains (2) summary
    COG0464
    Location:288 → 785
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    pfam00004
    Location:572 → 707
    AAA; ATPase family associated with various cellular activities (AAA)

  2. NM_135741.4 → NP_609585.1  uncharacterized protein Dmel_CG5776, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609585.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VK63
    Related
    FBpp0079988
    Conserved Domains (2) summary
    COG0464
    Location:288 → 785
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    pfam00004
    Location:572 → 707
    AAA; ATPase family associated with various cellular activities (AAA)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VK63 Q9VK63

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