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CG6712 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34631, updated on 9-Dec-2024

Summary

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Official Symbol
CG6712provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032408
Locus tag
Dmel_CG6712
See related
AllianceGenome:FB:FBgn0032408
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6712; ORF2
Summary
Predicted to enable RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in neuroblasts; nurse cell; organism; ovary; and presumptive embryonic/larval digestive system. Orthologous to human RPF1 (ribosome production factor 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG6712 in Genome Data Viewer
Location:
33C4-33C4; 2-46 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12095176..12096511, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12095176..12096511, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44593 Neighboring gene long non-coding RNA:CR44594 Neighboring gene Peroxin 19 Neighboring gene Methyltransferase 2 Neighboring gene Ced-12 Neighboring gene patsas

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries. Lyko F, et al. Mech Dev, 2000 Jul. PMID 10906465
  2. The archaeal homolog of the Imp4 protein, a eukaryotic U3 snoRNP component. Mayer C, et al. Trends Biochem Sci, 2001 Mar. PMID 11246005
  3. The eukaryotic DNMT2 genes encode a new class of cytosine-5 DNA methyltransferases. Tang LY, et al. J Biol Chem, 2003 Sep 5. PMID 12819212
  4. PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. Ciurciu A, et al. PLoS Genet, 2013 Oct. PMID 24204300, Free PMC Article
  5. A genome-wide RNAi screen reveals multiple regulators of caspase activation. Yi CH, et al. J Cell Biol, 2007 Nov 19. PMID 17998402, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables rRNA primary transcript binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in maturation of 5.8S rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6712-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    12095176..12096511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058131.5 → NP_477479.1  uncharacterized protein Dmel_CG6712 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477479.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VKB4
    Related
    FBpp0079946
    Conserved Domains (1) summary
    smart00879
    Location:188 → 358
    Brix; The Brix domain is found in a number of eukaryotic proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VKB4.1 Q9VKB4

Gene LinkOut

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Chemical Information
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