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Rab3-GAP - Rab3 GTPase activating protein

Predicted to enable small GTPase binding activity. Predicted to contribute to enzyme regulator activity. Involved in several processes, including macroautophagy; modulation of chemical synaptic transmission; and positive regulation of GTPase activity. Located in axon; presynaptic membrane; and vacuole. Is expressed in spermatozoon. Used to study Warburg micro syndrome. Human ortholog(s) of this gene implicated in Martsolf syndrome and Warburg micro syndrome 2. Orthologous to human RAB3GAP2 (RAB3 GTPase activating non-catalytic protein subunit 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa