JhI-21 - Juvenile hormone Inducible-21
Predicted to enable L-amino acid transmembrane transporter activity. Involved in several processes, including L-leucine import across plasma membrane; cellular response to L-leucine; and positive regulation of insulin secretion. Predicted to be located in membrane. Is expressed in several structures, including adult head; embryonic/larval motor neurons; embryonic/larval neuromuscular junction; ganglia; and larval central nervous system. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; hepatocellular carcinoma; and lung squamous cell carcinoma. Orthologous to several human genes including SLC7A5 (solute carrier family 7 member 5). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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