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CG6770 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34621, updated on 9-Dec-2024

Summary

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Official Symbol
CG6770provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032400
Locus tag
Dmel_CG6770
See related
AllianceGenome:FB:FBgn0032400
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO02059370.25; CT21019; Dmel\CG6770; p8
Summary
Predicted to be involved in negative regulation of cell cycle; negative regulation of cell population proliferation; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including NUPR1 (nuclear protein 1, transcriptional regulator). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG6770 in Genome Data Viewer
Location:
33B11-33B11; 2-45 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12045343..12046118, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12045343..12046118, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46070 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44589 Neighboring gene Promyelocytic leukemia zinc finger

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin. Bülow MH, et al. PLoS One, 2010 Dec 31. PMID 21217822, Free PMC Article
  2. The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology, and Influences Locomotor Activity in Drosophila Larvae. Ziegler AB, et al. Sci Rep, 2016 Jan 25. PMID 26805723, Free PMC Article
  3. Dietary Adaptation of Microbiota in Drosophila Requires NF-κB-Dependent Control of the Translational Regulator 4E-BP. Vandehoef C, et al. Cell Rep, 2020 Jun 9. PMID 32521261, Free PMC Article
  4. Forkhead, a new cross regulator of metabolism and innate immunity downstream of TOR in Drosophila. Varma D, et al. J Insect Physiol, 2014 Oct. PMID 24842780
  5. Differences in Postmating Transcriptional Responses between Conspecific and Heterospecific Matings in Drosophila. Ahmed-Braimah YH, et al. Mol Biol Evol, 2021 Mar 9. PMID 33035303, Free PMC Article

See all (55) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in negative regulation of cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6770-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    12045343..12046118 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135695.2 → NP_609539.1  uncharacterized protein Dmel_CG6770 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609539.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VKC5
    Related
    FBpp0079890
    Conserved Domains (1) summary
    pfam10195
    Location:3 → 55
    Phospho_p8; DNA-binding nuclear phosphoprotein p8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VKC5 Q9VKC5

Gene LinkOut

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