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sala spalt-adjacent [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34570, updated on 9-Dec-2024

Summary

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Official Symbol
salaprovided by FlyBase
Official Full Name
spalt-adjacentprovided by FlyBase
Primary source
FLYBASE:FBgn0003313
Locus tag
Dmel_CG4922
See related
AllianceGenome:FB:FBgn0003313
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE40068; CG4922; chr2L:11486634..11486740; Dmel\CG4922; nsal; sal; Sal; Sala
Summary
Involved in gastrulation. Is expressed in several structures, including anlage in statu nascendi; antennal anlage; epidermis; head epidermis primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See sala in Genome Data Viewer
Location:
32F2-32F2; 2-44 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11484707..11486949)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11484707..11486949)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene spalt major Neighboring gene long non-coding RNA:CR46454 Neighboring gene uncharacterized protein Neighboring gene Component of oligomeric golgi complex 8 Neighboring gene spatzle 4 Neighboring gene Discs large 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The homeotic gene spalt (sal) evolved during Drosophila speciation. Reuter D, et al. Proc Natl Acad Sci U S A, 1989 Jul. PMID 2568636, Free PMC Article
  2. Identification of target genes of the homeotic gene Antennapedia by enhancer detection. Wagner-Bernholz JT, et al. Genes Dev, 1991 Dec. PMID 1684334
  3. Molecular characterization of spalt, a homeotic gene required for head and tail development in the Drosophila embryo. Frei E, et al. EMBO J, 1988 Jan. PMID 16453821, Free PMC Article
  4. The spalt-related gene of Drosophila melanogaster is a member of an ancient gene family, defined by the adjacent, region-specific homeotic gene spalt. Barrio R, et al. Dev Genes Evol, 1996 Dec. PMID 24173589
  5. spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo. Kühnlein RP, et al. EMBO J, 1994 Jan 1. PMID 7905822, Free PMC Article

See all (55) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. analysis of the enhancer that drives expression of the Drosophila gene spalt in the wing blade
    Title: Regulation of spalt expression in the Drosophila wing blade in response to the Decapentaplegic signaling pathway.
  2. Our results indicate that these genes exhibited temporal and spatially restricted patterns of expression in developing embryos, and moreover, their transcripts were detected in cells that undergo morphological changes during the gastrulation stage
    Title: Identification of genes expressed during Drosophila melanogaster gastrulation by using subtractive hybridization.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in gastrulation IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
spalt-adjacent
Names
CG4922-PA
CG4922-PC
not-spalt
sal adjacent
sala-PA
sala-PC
spalt
spalt accessory

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    11484707..11486949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259056.1 → NP_001245985.1  spalt-adjacent, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245985.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21750, Q9VKH1
    UniProtKB/TrEMBL
    M9NCT5

  2. NM_078825.4 → NP_523549.1  spalt-adjacent, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523549.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P21750, Q9VKH1
    UniProtKB/TrEMBL
    M9NCT5
    Related
    FBpp0079824
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NCT5 M9NCT5
P21750.2 P21750

Gene LinkOut

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