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l(2)gd1 - lethal (2) giant discs 1

Enables phosphatidylinositol phosphate binding activity. Involved in several processes, including female germ-line stem cell asymmetric division; imaginal disc-derived wing vein morphogenesis; and positive regulation of intralumenal vesicle formation. Located in cytoplasmic side of apical plasma membrane and endosome membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 3 and intellectual disability. Orthologous to several human genes including CC2D1A (coiled-coil and C2 domain containing 1A). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa