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CG17097 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34461, updated on 9-Dec-2024

Summary

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Official Symbol
CG17097provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0265264
Locus tag
Dmel_CG17097
See related
AllianceGenome:FB:FBgn0265264
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-SAGE:Wang-018; Dmel\CG17097
Summary
Enables serine hydrolase activity. Involved in sexual reproduction. Located in extracellular space. Is expressed in adult head. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPK (lipase family member K); LIPM (lipase family member M); and LIPN (lipase family member N). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG17097 in Genome Data Viewer
Location:
32A2-32A2; 2-43 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10646415..10650152)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10646415..10650152)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44580 Neighboring gene doublefault

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Orthology, function and evolution of accessory gland proteins in the Drosophila repleta group. Almeida FC, et al. Genetics, 2009 Jan. PMID 19015541, Free PMC Article
  2. Inference of positive and negative selection on the 5' regulatory regions of Drosophila genes. Kohn MH, et al. Mol Biol Evol, 2004 Feb. PMID 14660692
  3. Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila. Swanson WJ, et al. Proc Natl Acad Sci U S A, 2001 Jun 19. PMID 11404480, Free PMC Article
  4. Retention of Ejaculate by Drosophila melanogaster Females Requires the Male-Derived Mating Plug Protein PEBme. Avila FW, et al. Genetics, 2015 Aug. PMID 26058847, Free PMC Article
  5. Comparative structural modeling and inference of conserved protein classes in Drosophila seminal fluid. Mueller JL, et al. Proc Natl Acad Sci U S A, 2004 Sep 14. PMID 15345744, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine hydrolase activity HDA PubMed 
enables triacylglycerol lipase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in lipid metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in sexual reproduction HEP PubMed 
involved_in sexual reproduction IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space HDA PubMed 
located_in extracellular space ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG17097-PB
anon-SAGE:Wang-018
NP_609429.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10646415..10650152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135585.3 → NP_609429.1  uncharacterized protein Dmel_CG17097 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609429.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E2QCS7
    Related
    FBpp0290352
    Conserved Domains (3) summary
    COG0596
    Location:746 → 1061
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    pfam04083
    Location:726 → 780
    Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
    pfam12695
    Location:762 → 899
    Abhydrolase_5; Alpha/beta hydrolase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E2QCS7 E2QCS7

Gene LinkOut

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