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CG7329 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34457, updated on 9-Dec-2024

Summary

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Official Symbol
CG7329provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032271
Locus tag
Dmel_CG7329
See related
AllianceGenome:FB:FBgn0032271
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7329; ORE-4
Summary
Predicted to enable triacylglycerol lipase activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPK (lipase family member K); LIPM (lipase family member M); and LIPN (lipase family member N). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7329 in Genome Data Viewer
Location:
32A2-32A2; 2-43 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10629352..10638471, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10629352..10638471, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Tripartite motif containing 9 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45351 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of unannotated exons of low abundance transcripts in Drosophila melanogaster and cloning of a new serine protease gene upregulated upon injury. Maia RM, et al. BMC Genomics, 2007 Jul 24. PMID 17650329, Free PMC Article
  2. Comparative and functional genomics of lipases in holometabolous insects. Horne I, et al. Insect Biochem Mol Biol, 2009 Aug. PMID 19540341
  3. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
  4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables triacylglycerol lipase activity ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7329-PA
CG7329-PB
NP_001260357.1
NP_609425.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10629352..10638471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273428.2 → NP_001260357.1  uncharacterized protein Dmel_CG7329, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260357.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3X7, Q9VKT2
    Conserved Domains (3) summary
    pfam00561
    Location:77 → 371
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam04083
    Location:42 → 96
    Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
    cl21494
    Location:73 → 239
    Abhydrolase; alpha/beta hydrolases

  2. NM_135581.2 → NP_609425.1  uncharacterized protein Dmel_CG7329, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609425.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3X7, Q9VKT2
    Related
    FBpp0079720
    Conserved Domains (3) summary
    pfam00561
    Location:77 → 371
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam04083
    Location:42 → 96
    Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
    cl21494
    Location:73 → 239
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T3X7 Q8T3X7
Q9VKT2 Q9VKT2

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