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CG5708 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34361, updated on 4-Jan-2025

Summary

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Official Symbol
CG5708provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032196
Locus tag
Dmel_CG5708
See related
AllianceGenome:FB:FBgn0032196
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5708
Summary
Predicted to be involved in leg disc development. Predicted to be located in nucleus. Is expressed in wing hinge primordium and wing pouch. Orthologous to human LMO4 (LIM domain only 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG5708 in Genome Data Viewer
Location:
31B1-31B1; 2-40 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10224457..10226808, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10224457..10226808, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Proteasome alpha6 subunit Neighboring gene Bcs1 chaperone Neighboring gene ovaries absent Neighboring gene eukaryotic translation elongation factor 1 delta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development. Pueyo JI, et al. Development, 2004 Jul. PMID 15175252
  2. An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP. Fiedler M, et al. Elife, 2015 Aug 27. PMID 26312500, Free PMC Article
  3. The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis. She M, et al. Front Cardiovasc Med, 2021. PMID 33681304, Free PMC Article
  4. Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover. Huang S, et al. PLoS Biol, 2013 Nov. PMID 24302888, Free PMC Article
  5. Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome. Grimberg KB, et al. Mol Cell Biol, 2011 Feb. PMID 21149573, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in leg disc development ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5708-PA
CG5708-PB
CG5708-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10224457..10226808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298870.1 → NP_001285799.1  uncharacterized protein Dmel_CG5708, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285799.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VL21
    Conserved Domains (2) summary
    cd09386
    Location:78 → 132
    LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
    cl02475
    Location:142 → 212
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. NM_164893.2 → NP_723534.1  uncharacterized protein Dmel_CG5708, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723534.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VL21
    Related
    FBpp0079546
    Conserved Domains (2) summary
    cd09386
    Location:78 → 132
    LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
    cl02475
    Location:142 → 212
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. NM_135515.2 → NP_609359.1  uncharacterized protein Dmel_CG5708, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609359.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VL21
    Related
    FBpp0079545
    Conserved Domains (2) summary
    cd09386
    Location:78 → 132
    LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
    cl02475
    Location:142 → 212
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VL21 Q9VL21

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