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Trs23 TRAPP subunit 23 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34197, updated on 4-Jan-2025

Summary

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Official Symbol
Trs23provided by FlyBase
Official Full Name
TRAPP subunit 23provided by FlyBase
Primary source
FLYBASE:FBgn0260861
Locus tag
Dmel_CG9298
See related
AllianceGenome:FB:FBgn0260861
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9298; Dmel\CG9298; TRAPPC4; TRS23; Trs23p
Summary
Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Part of TRAPPII protein complex and TRAPPIII protein complex. Is expressed in adult head. Orthologous to human TRAPPC4 (trafficking protein particle complex subunit 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Trs23 in Genome Data Viewer
Location:
29E3-29E4; 2-33 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8686231..8687052)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8686231..8687052)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene transfer RNA:Aspartic acid-GTC 1-9 Neighboring gene uncharacterized protein Neighboring gene Prenyl-binding protein Neighboring gene Hepatocyte nuclear factor 4 Neighboring gene antisense RNA:CR44992 Neighboring gene Catalase B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1. Galindo A, et al. EMBO J, 2021 Jun 15. PMID 34018214, Free PMC Article
  2. TRAPPII is required for cleavage furrow ingression and localization of Rab11 in dividing male meiotic cells of Drosophila. Robinett CC, et al. J Cell Sci, 2009 Dec 15. PMID 19934220, Free PMC Article
  3. Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Palanker L, et al. Cell Metab, 2009 Mar. PMID 19254568, Free PMC Article
  4. The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases. Riedel F, et al. J Cell Biol, 2018 Feb 5. PMID 29273580, Free PMC Article
  5. Fast and effective prediction of microRNA/target duplexes. Rehmsmeier M, et al. RNA, 2004 Oct. PMID 15383676, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to guanyl-nucleotide exchange factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in Golgi vesicle transport IC
Inferred by Curator
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of TRAPP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TRAPP complex IEA
Inferred from Electronic Annotation
more info
  
part_of TRAPP complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of TRAPPII protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of TRAPPIII protein complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
TRAPP subunit 23
Names
CG9298-PA
TRAPP subunit 23 ortholog
Trs23-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8686231..8687052
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135403.2 → NP_609247.1  TRAPP subunit 23 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609247.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VLI9
    Related
    FBpp0079332
    Conserved Domains (2) summary
    cd14856
    Location:99 → 205
    TRAPPC4_synbindin; Trafficking protein particle complex subunit 4
    cl00117
    Location:38 → 102
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLI9 Q9VLI9

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