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Bace - beta-site APP-cleaving enzyme

Enables aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. Predicted to be involved in apoptotic process and proteolysis. Located in axon and neuronal cell body. Is expressed in adult brain; adult brain cell body rind; adult head; lamina; and medulla. Orthologous to several human genes including CTSE (cathepsin E); PGA3 (pepsinogen A3); and PGA4 (pepsinogen A4). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Bace

NCBI Orthologs

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Species Gene Architecture aa