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CG13392 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34157, updated on 4-Jan-2025

Summary

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Official Symbol
CG13392provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032033
Locus tag
Dmel_CG13392
See related
AllianceGenome:FB:FBgn0032033
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
2L11; Dmel\CG13392; dTMEM126B
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Is active in mitochondrion. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 29 and optic atrophy 7. Orthologous to human TMEM126A (transmembrane protein 126A) and TMEM126B (transmembrane protein 126B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG13392 in Genome Data Viewer
Location:
29B3-29B4; 2-31 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8381821..8382807, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8381821..8382807, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Alanyl-tRNA synthetase Neighboring gene Reduction in Cnn dots 4 Neighboring gene Defender against apoptotic cell death 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis. Murari A, et al. iScience, 2021 Aug 20. PMID 34386730, Free PMC Article
  2. Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. Yatsenko AS, et al. BMC Med, 2020 Jan 21. PMID 31959160, Free PMC Article
  3. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
  4. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
  5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG13392-PA
CG13392-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8381821..8382807 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273318.1 → NP_001260247.1  uncharacterized protein Dmel_CG13392, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260247.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VLM7
    Conserved Domains (1) summary
    pfam07114
    Location:39 → 207
    DUF1370; Protein of unknown function (DUF1370)

  2. NM_135376.2 → NP_609220.1  uncharacterized protein Dmel_CG13392, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609220.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VLM7
    Related
    FBpp0079325
    Conserved Domains (1) summary
    pfam07114
    Location:39 → 207
    DUF1370; Protein of unknown function (DUF1370)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLM7 Q9VLM7

Gene LinkOut

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