CG7840 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG7840provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0032014
Locus tag: Dmel_CG7840
See related: AllianceGenome:FB:FBgn0032014
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: cg7840; Dmel\CG7840
Summary: Predicted to enable 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity and polyprenol reductase activity. Predicted to be involved in dolichol biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; and polyprenol catabolic process. Predicted to be active in endoplasmic reticulum. Is expressed in organism. Human ortholog(s) of this gene implicated in Kahrizi syndrome and congenital disorder of glycosylation Iq. Orthologous to human SRD5A3 (steroid 5 alpha-reductase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (8305586..8306741)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (8305586..8306741)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity	ISS Inferred from Sequence or Structural Similarity more info
enables polyprenal reductase activity	ISS Inferred from Sequence or Structural Similarity more info
enables polyprenol reductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables polyprenol reductase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in dolichol biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dolichol biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in dolichol metabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in dolichol-linked oligosaccharide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dolichol-linked oligosaccharide biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in dolichol-linked oligosaccharide biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in polyprenol catabolic process	ISS Inferred from Sequence or Structural Similarity more info