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CG8475 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34114, updated on 4-Jan-2025

Summary

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Official Symbol
CG8475provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031995
Locus tag
Dmel_CG8475
See related
AllianceGenome:FB:FBgn0031995
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8475
Summary
Predicted to enable calmodulin binding activity. Predicted to be involved in positive regulation of glycogen catabolic process. Predicted to be part of phosphorylase kinase complex. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in glycogen storage disease IXb. Orthologous to human PHKB (phosphorylase kinase regulatory subunit beta). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG8475 in Genome Data Viewer
Location:
28F1-28F1; 2-30 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8190808..8196918, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8190808..8196918, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene piezo Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44116 Neighboring gene uncharacterized protein Neighboring gene Post-GPI attachment to proteins 5 Neighboring gene Sodium/solute co-transporter-like 5A11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster. Yu KE, et al. Mol Cells, 2018 Feb 28. PMID 29429152, Free PMC Article
  2. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
  3. Affinity Density: a novel genomic approach to the identification of transcription factor regulatory targets. Hazelett DJ, et al. Bioinformatics, 2009 Jul 1. PMID 19401399, Free PMC Article
  4. Prediction and verification of microRNA targets by MovingTargets, a highly adaptable prediction method. Burgler C, et al. BMC Genomics, 2005 Jun 8. PMID 15943864, Free PMC Article
  5. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of glycogen catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of phosphorylase kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8475-PA
CG8475-PB
CG8475-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8190808..8196918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273301.1 → NP_001260230.1  uncharacterized protein Dmel_CG8475, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260230.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCI5
    Conserved Domains (1) summary
    pfam00723
    Location:49 → 468
    Glyco_hydro_15; Glycosyl hydrolases family 15

  2. NM_135345.3 → NP_609189.2  uncharacterized protein Dmel_CG8475, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609189.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F9VMG4, Q8IPG3, Q8SXP4, Q9VLS1
    Related
    FBpp0079254
    Conserved Domains (1) summary
    pfam00723
    Location:49 → 468
    Glyco_hydro_15; Glycosyl hydrolases family 15

  3. NM_164797.3 → NP_723356.1  uncharacterized protein Dmel_CG8475, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723356.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VLS1
    Related
    FBpp0079255
    Conserved Domains (1) summary
    pfam00723
    Location:49 → 468
    Glyco_hydro_15; Glycosyl hydrolases family 15
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PCI5 M9PCI5
Q9VLS1.2 Q9VLS1

Gene LinkOut

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