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CG8673 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34105, updated on 4-Jan-2025

Summary

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Official Symbol
CG8673provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031986
Locus tag
Dmel_CG8673
See related
AllianceGenome:FB:FBgn0031986
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
dbeta3GnT; Dmel\CG8673; GalT5
Summary
Predicted to enable UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in membrane. Predicted to be active in Golgi membrane. Is expressed in adult head. Orthologous to several human genes including B3GALT2 (beta-1,3-galactosyltransferase 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG8673 in Genome Data Viewer
Location:
28E7-28E7; 2-30 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8124329..8125799)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8124329..8125799)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Basigin Neighboring gene monensin sensitivity 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Phosphatidic Acid Phospholipase A1 Neighboring gene mir-4984 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis. Schwientek T, et al. J Biol Chem, 2002 Sep 6. PMID 12130651
  2. Functional variants identify sex-specific genes and pathways in Alzheimer's Disease. Bourquard T, et al. Nat Commun, 2023 May 13. PMID 37179358, Free PMC Article
  3. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
  4. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Anholt RR, et al. Behav Genet, 2001 Jan. PMID 11529271
  5. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8673-PA
NP_609182.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8124329..8125799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135338.2 → NP_609182.1  uncharacterized protein Dmel_CG8673 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609182.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DN04, Q9VLT0
    Related
    FBpp0079197
    Conserved Domains (1) summary
    cl21608
    Location:186 → 374
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLT0 Q9VLT0

Gene LinkOut

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