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CG7231 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34086, updated on 9-Dec-2024

Summary

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Official Symbol
CG7231provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031968
Locus tag
Dmel_CG7231
See related
AllianceGenome:FB:FBgn0031968
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7231
Summary
Predicted to be active in extracellular space. Is expressed in adult head. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to several human genes including FAM151B (family with sequence similarity 151 member B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG7231 in Genome Data Viewer
Location:
28D3-28D3; 2-29 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7983946..7986785)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7983946..7986785)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Serpin 28Da Neighboring gene Serpin 28Db Neighboring gene Sno oncogene Neighboring gene antisense RNA:CR44996 Neighboring gene peste Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. Ghosh S, et al. Hum Mol Genet, 2004 Sep 15. PMID 15254017
  2. [LTR retrotransposons as a source of promoters in the Drosophila genome]. Makunin IV, et al. Genetika, 2010 Sep. PMID 21061618
  3. Drosophila SnoN modulates growth and patterning by antagonizing TGF-beta signalling. Ramel MC, et al. Mech Dev, 2007 Apr. PMID 17289352
  4. dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2. Takaesu NT, et al. Genetics, 2006 Nov. PMID 16951053, Free PMC Article
  5. Characterization of dSnoN and its relationship to Decapentaplegic signaling in Drosophila. Barrio R, et al. Dev Biol, 2007 Jun 1. PMID 17434471

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7231-PC
CG7231-PD
CG7231-PE
CG7231-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7983946..7986785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164776.4 → NP_723327.1  uncharacterized protein Dmel_CG7231, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723327.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G7H7Z7, Q9VLU9
    Related
    FBpp0289422
    Conserved Domains (1) summary
    pfam10223
    Location:63 → 319
    DUF2181; Uncharacterized conserved protein (DUF2181)

  2. NM_135323.5 → NP_609167.3  uncharacterized protein Dmel_CG7231, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609167.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    G7H7Z7, Q8IPH1, Q8MQP2
    Conserved Domains (1) summary
    pfam10223
    Location:8 → 261
    DUF2181; Uncharacterized conserved protein (DUF2181)

  3. NM_001259004.1 → NP_001245933.1  uncharacterized protein Dmel_CG7231, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245933.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G7H7Z7, Q8IPH1, Q8MQP2
    Conserved Domains (1) summary
    pfam10223
    Location:8 → 261
    DUF2181; Uncharacterized conserved protein (DUF2181)

  4. NM_205923.3 → NP_995645.1  uncharacterized protein Dmel_CG7231, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995645.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G7H7Z7, Q8IPH1, Q8MQP2
    Conserved Domains (1) summary
    pfam10223
    Location:8 → 261
    DUF2181; Uncharacterized conserved protein (DUF2181)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MQP2 Q8MQP2
Q9VLU9 Q9VLU9

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