Sumo - Small ubiquitin like modifier
Enables protein tag activity. Involved in several processes, including dorsal appendage formation; neuron projection morphogenesis; and positive regulation of signal transduction. Located in condensed chromosome; midbody; and nucleolus. Part of outer kinetochore. Is expressed in several structures, including adult head; adult heart; embryonic cortex; germarium; and germline cell. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus 5. Orthologous to human SUMO2 (small ubiquitin like modifier 2); SUMO3 (small ubiquitin like modifier 3); and SUMO4 (small ubiquitin like modifier 4). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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