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Nhe3 - Na[+]/H[+] hydrogen exchanger 3

Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Located in perinuclear region of cytoplasm. Is expressed in adult central nervous system; adult head; and organism. Human ortholog(s) of this gene implicated in Christianson syndrome; X-linked intellectual developmental disorder 108; and autistic disorder. Orthologous to several human genes including SLC9A9 (solute carrier family 9 member A9). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa