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Oatp26F Organic anion transporting polypeptide 26F [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33927, updated on 4-Jan-2025

Summary

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Official Symbol
Oatp26Fprovided by FlyBase
Official Full Name
Organic anion transporting polypeptide 26Fprovided by FlyBase
Primary source
FLYBASE:FBgn0051634
Locus tag
Dmel_CG31634
See related
AllianceGenome:FB:FBgn0051634
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11332; CG13767; CG18784; CG31634; Dmel\CG31634; oatp 26F; oatp26F
Summary
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport and transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including ganglia; larval nervous system; mesectoderm; midline primordium; and ventral midline of embryo. Orthologous to human SLCO4A1 (solute carrier organic anion transporter family member 4A1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Oatp26F in Genome Data Viewer
Location:
26F3-26F3; 2-21 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6625138..6632407, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6625138..6632407, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44913 Neighboring gene Dpr-interacting protein iota Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Transport and Golgi organization 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Essential functions of mosquito ecdysone importers in development and reproduction. Hun LV, et al. Proc Natl Acad Sci U S A, 2022 Jun 21. PMID 35696563, Free PMC Article
  2. Resolution of the insect ouabain paradox. Torrie LS, et al. Proc Natl Acad Sci U S A, 2004 Sep 14. PMID 15347816, Free PMC Article
  3. Common motifs shared by conserved enhancers of Drosophila midline glial genes. Fulkerson E, et al. J Exp Zool B Mol Dev Evol, 2011 Jan 15. PMID 21154525
  4. An Oatp transporter-mediated steroid sink promotes tumor-induced cachexia in Drosophila. Santabárbara-Ruiz P, et al. Dev Cell, 2021 Oct 11. PMID 34610327
  5. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Okamoto N, et al. Dev Cell, 2018 Nov 5. PMID 30293839, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables organic anion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in organic anion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
organic anion transporting polypeptide 26F
Names
CG31634-PA
Oatp26F-PA
organic anion transporter protein 26f

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    6625138..6632407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135211.3 → NP_609055.2  organic anion transporting polypeptide 26F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609055.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SY02, Q9I7P0
    Related
    FBpp0078956
    Conserved Domains (3) summary
    cd06174
    Location:69 → 318
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:476 → 529
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    pfam03137
    Location:66 → 647
    OATP; Organic Anion Transporter Polypeptide (OATP) family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SY02 Q8SY02

Gene LinkOut

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