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retm real-time [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33899, updated on 9-Dec-2024

Summary

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Official Symbol
retmprovided by FlyBase
Official Full Name
real-timeprovided by FlyBase
Primary source
FLYBASE:FBgn0031814
Locus tag
Dmel_CG9528
See related
AllianceGenome:FB:FBgn0031814
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9528; Dmel\CG9528
Summary
Located in mitochondrion. Is expressed in adult head. Orthologous to several human genes including SEC14L5 (SEC14 like lipid binding 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See retm in Genome Data Viewer
Location:
26D4-26D5; 2-20 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6448464..6455929, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6448464..6455929, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Fic domain-containing protein Neighboring gene Acyl-CoA oxidase 3 Neighboring gene farjavit Neighboring gene Ring finger and CHY zinc finger domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel family of mitochondrial proteins is represented by the Drosophila genes slmo, preli-like and real-time. Dee CT, et al. Dev Genes Evol, 2005 May. PMID 15700158
  2. PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail. Jiang K, et al. PLoS Biol, 2016 Feb. PMID 26863604, Free PMC Article
  3. RNA editing in Drosophila melanogaster: New targets and functional consequences. Stapleton M, et al. RNA, 2006 Nov. PMID 17018572, Free PMC Article
  4. Drosophila glia: Few cell types and many conserved functions. Yildirim K, et al. Glia, 2019 Jan. PMID 30443934
  5. Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. Marcogliese PC, et al. Cell Rep, 2022 Mar 15. PMID 35294868, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
real-time
Names
CG9528-PA
CG9528-PB
CG9528-PC
retm-PA
retm-PB
retm-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    6448464..6455929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298743.1 → NP_001285672.1  real-time, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285672.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95U56, Q9VMD6
    UniProtKB/TrEMBL
    B5RIN0
    Conserved Domains (3) summary
    smart01100
    Location:222 → 268
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:293 → 456
    CRAL_TRIO; CRAL/TRIO domain
    pfam04707
    Location:17 → 173
    PRELI; PRELI-like family

  2. NM_135184.4 → NP_609028.2  real-time, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609028.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95U56, Q9VMD6
    UniProtKB/TrEMBL
    B5RIN0
    Related
    FBpp0078902
    Conserved Domains (3) summary
    smart01100
    Location:222 → 268
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:293 → 456
    CRAL_TRIO; CRAL/TRIO domain
    pfam04707
    Location:17 → 173
    PRELI; PRELI-like family

  3. NM_001273203.2 → NP_001260132.1  real-time, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260132.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PB50
    Conserved Domains (3) summary
    smart01100
    Location:222 → 268
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:293 → 456
    CRAL_TRIO; CRAL/TRIO domain
    pfam04707
    Location:17 → 173
    PRELI; PRELI-like family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B5RIN0 B5RIN0
M9PB50 M9PB50
Q9VMD6.2 Q9VMD6

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