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creb3l1 cAMP responsive element binding protein 3-like 1 [ Danio rerio (zebrafish) ]

Gene ID: 338317, updated on 9-Dec-2024

Summary

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Official Symbol
creb3l1provided by ZNC
Official Full Name
cAMP responsive element binding protein 3-like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030219-181
See related
Ensembl:ENSDARG00000015793 AllianceGenome:ZFIN:ZDB-GENE-030219-181
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa98d12; id:ibd2573; id:ibd5131; wu:fa98d12
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cAMP response element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in axial chorda mesoderm; notochord; shield; and tail bud. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to human CREB3L1 (cAMP responsive element binding protein 3 like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See creb3l1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (38897932..38954874)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (38626667..38683616)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene zgc:110699 Neighboring gene harbinger transposase derived 1 Neighboring gene PHD finger protein 21Aa Neighboring gene uncharacterized LOC101882371 Neighboring gene diacylglycerol kinase, zeta a Neighboring gene uncharacterized LOC137496188

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cAMP response element binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cyclic AMP-responsive element-binding protein 3-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243038.1 → NP_001229967.1  cyclic AMP-responsive element-binding protein 3-like protein 1

    Status: VALIDATED

    Source sequence(s)
    BX957256, CR382325
    UniProtKB/TrEMBL
    A0A0R4IKX3, A0A8M1P3X6
    Conserved Domains (1) summary
    cd14689
    Location:273 → 327
    bZIP_CREB3; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 3 (CREB3) and similar proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    38897932..38954874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005168966.4 → XP_005169023.1  cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGW2, E7FCG3
    Related
    ENSDARP00000012411.6, ENSDART00000024330.9
    Conserved Domains (1) summary
    cd14689
    Location:296 → 350
    bZIP_CREB3; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 3 (CREB3) and similar proteins: a DNA-binding and dimerization domain

  2. XM_009303310.3 → XP_009301585.1  cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AUC8
    Related
    ENSDARP00000134652.2, ENSDART00000172251.2
    Conserved Domains (1) summary
    cd14689
    Location:296 → 350
    bZIP_CREB3; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 3 (CREB3) and similar proteins: a DNA-binding and dimerization domain
Nucleotide Protein Strain
Heading Accession and Version

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