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CG7236 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33798, updated on 9-Dec-2024

Summary

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Official Symbol
CG7236provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031730
Locus tag
Dmel_CG7236
See related
AllianceGenome:FB:FBgn0031730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC018104; CG7236/Cdk1l; Dmel\CG7236; KKIALRE
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human CDKL1 (cyclin dependent kinase like 1) and CDKL4 (cyclin dependent kinase like 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7236 in Genome Data Viewer
Location:
25F3-25F3; 2-17 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5706374..5713791)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5706374..5713791)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44819 Neighboring gene long non-coding RNA:CR44820 Neighboring gene antisense RNA:CR44818 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology. Liu T, et al. Genome Biol, 2009. PMID 19265526, Free PMC Article
  2. Drosophila septin interacting protein 1 regulates neurogenesis in the early developing larval brain. Wei JY, et al. Sci Rep, 2022 Jan 7. PMID 34997175, Free PMC Article
  3. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. Yin Z, et al. BMC Bioinformatics, 2008 Jun 5. PMID 18534020, Free PMC Article
  4. Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa. Liu J, et al. Mol Biol Evol, 2000 Jul. PMID 10889219
  5. Interallelic Transcriptional Enhancement as an in Vivo Measure of Transvection in Drosophila melanogaster. Noble GP, et al. G3 (Bethesda), 2016 Oct 13. PMID 27489208, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables cyclin-dependent protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7236-PB
CG7236-PC
CG7236-PD
CG7236-PE
NP_001188702.1
NP_001285634.1
NP_001285635.1
NP_608950.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5706374..5713791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298706.1 → NP_001285635.1  uncharacterized protein Dmel_CG7236, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285635.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JD86
    Conserved Domains (1) summary
    cd07847
    Location:31 → 318
    STKc_CDKL1_4; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 1 and 4

  2. NM_135106.4 → NP_608950.3  uncharacterized protein Dmel_CG7236, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608950.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMN3
    Conserved Domains (2) summary
    cd07847
    Location:48 → 335
    STKc_CDKL1_4; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 1 and 4
    pfam00069
    Location:50 → 335
    Pkinase; Protein kinase domain

  3. NM_001298705.1 → NP_001285634.1  uncharacterized protein Dmel_CG7236, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285634.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2J708
    Conserved Domains (1) summary
    cd07847
    Location:22 → 309
    STKc_CDKL1_4; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 1 and 4

  4. NM_001201773.2 → NP_001188702.1  uncharacterized protein Dmel_CG7236, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188702.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MRD8
    Conserved Domains (2) summary
    cd07847
    Location:45 → 332
    STKc_CDKL1_4; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 1 and 4
    pfam00069
    Location:47 → 332
    Pkinase; Protein kinase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9MRD8 M9MRD8
Q9VMN3 Q9VMN3
X2J708 X2J708
X2JD86 X2JD86

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