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CG12511 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33797, updated on 4-Jan-2025

Summary

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Official Symbol
CG12511provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031729
Locus tag
Dmel_CG12511
See related
AllianceGenome:FB:FBgn0031729
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12511
Summary
Predicted to be involved in autophagy of mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC1 (FUN14 domain containing 1) and FUNDC2 (FUN14 domain containing 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG12511 in Genome Data Viewer
Location:
25F2-25F2; 2-17 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5678582..5679499)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5678582..5679499)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44821 Neighboring gene Heat shock protein 60C Neighboring gene long non-coding RNA:CR44819 Neighboring gene long non-coding RNA:CR44820 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Halfon MS, et al. Genome Res, 2002 Jul. PMID 12097338, Free PMC Article
  2. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
  3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  4. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12511-PB
CG12511-PC
CG12511-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5678582..5679499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298704.1 → NP_001285633.1  uncharacterized protein Dmel_CG12511, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285633.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B6IDP6
    Conserved Domains (1) summary
    pfam04930
    Location:13 → 109
    FUN14; FUN14 family

  2. NM_001258970.2 → NP_001245899.1  uncharacterized protein Dmel_CG12511, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245899.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B6IDP6
    Conserved Domains (1) summary
    pfam04930
    Location:13 → 109
    FUN14; FUN14 family

  3. NM_135105.3 → NP_608949.2  uncharacterized protein Dmel_CG12511, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608949.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMN4
    Conserved Domains (1) summary
    pfam04930
    Location:23 → 119
    FUN14; FUN14 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B6IDP6 B6IDP6
Q9VMN4 Q9VMN4

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