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DIP-eta Dpr-interacting protein eta [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33793, updated on 9-Dec-2024

Summary

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Official Symbol
DIP-etaprovided by FlyBase
Official Full Name
Dpr-interacting protein etaprovided by FlyBase
Primary source
FLYBASE:FBgn0031725
Locus tag
Dmel_CG14010
See related
AllianceGenome:FB:FBgn0031725
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
14010; CG14010; CT33567; DIPeta; Dmel\CG14010
Summary
Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection. Is expressed in optic lobe intrinsic columnar neurons. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to several human genes including IGLON5 (IgLON family member 5); NTM (neurotrimin); and OPCML (opioid binding protein/cell adhesion molecule like). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See DIP-eta in Genome Data Viewer
Location:
25F1-25F1; 2-17 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5601723..5617946, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5601723..5617946, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44795 Neighboring gene long non-coding RNA:CR44796 Neighboring gene Cytochrome P450 6a16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic Architecture of Natural Variation Underlying Adult Foraging Behavior That Is Essential for Survival of Drosophila melanogaster. Lee YCG, et al. Genome Biol Evol, 2017 May 1. PMID 28472322, Free PMC Article
  2. Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Cheng S, et al. Elife, 2019 Jan 28. PMID 30688651, Free PMC Article
  3. Classifying Protein-Protein Binding Affinity with Free-Energy Calculations and Machine Learning Approaches. Goulard Coderc de Lacam E, et al. J Chem Inf Model, 2024 Feb 12. PMID 38272021
  4. Drosophila TET acts with PRC1 to activate gene expression independently of its catalytic activity. Gilbert G, et al. Sci Adv, 2024 May 3. PMID 38701218, Free PMC Article
  5. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c5608668-5608581 mobile_element_type = transposon:INE-1{}5109

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in synapse organization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Dpr-interacting protein eta
Names
CG14010-PB
CG14010-PD
DIP-eta-PB
DIP-eta-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5601723..5617946 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135102.3 → NP_608946.3  Dpr-interacting protein eta, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608946.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MRF8, Q9VMN9
    Conserved Domains (3) summary
    cd00096
    Location:258 → 333
    Ig; Immunoglobulin domain
    smart00410
    Location:153 → 237
    IG_like; Immunoglobulin like
    cl11960
    Location:161 → 224
    Ig; Immunoglobulin domain

  2. NM_001201772.2 → NP_001188701.2  Dpr-interacting protein eta, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188701.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9MRF8, Q9VMN9
    Conserved Domains (3) summary
    cd00096
    Location:258 → 333
    Ig; Immunoglobulin domain
    smart00410
    Location:153 → 237
    IG_like; Immunoglobulin like
    cl11960
    Location:161 → 224
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VMN9 Q9VMN9

Gene LinkOut

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