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mRpL28 mitochondrial ribosomal protein L28 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33715, updated on 4-Jan-2025

Summary

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Official Symbol
mRpL28provided by FlyBase
Official Full Name
mitochondrial ribosomal protein L28provided by FlyBase
Primary source
FLYBASE:FBgn0031660
Locus tag
Dmel_CG3782
See related
AllianceGenome:FB:FBgn0031660
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3782; Dmel\CG3782; MRP-L28
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in adult head. Orthologous to human MRPL28 (mitochondrial ribosomal protein L28). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See mRpL28 in Genome Data Viewer
Location:
25B5-25B5; 2-14 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4973976..4975316)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4973976..4975316)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene RNA polymerase I and III subunit C Neighboring gene lethal (2) 05714 Neighboring gene uncharacterized protein Neighboring gene GDP-mannose 4,6-dehydratase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. Roos C, et al. J Biol Chem, 2002 Feb 1. PMID 11698403
  2. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article
  3. The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. Koc EC, et al. J Biol Chem, 2001 Nov 23. PMID 11551941
  4. Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Zou S, et al. Proc Natl Acad Sci U S A, 2000 Dec 5. PMID 11095759, Free PMC Article
  5. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
  
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of mitochondrial large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
mitochondrial ribosomal protein L28
Names
CG3782-PA
CG3782-PB
ecdysteroid regulated 16kd protein
mRpL28-PA
mRpL28-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4973976..4975316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273134.1 → NP_001260063.1  mitochondrial ribosomal protein L28, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260063.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SXZ1, Q9VMX0
    UniProtKB/TrEMBL
    A8E702

  2. NM_135043.4 → NP_608887.1  mitochondrial ribosomal protein L28, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608887.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SXZ1, Q9VMX0
    UniProtKB/TrEMBL
    A8E702
    Related
    FBpp0078635
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8E702 A8E702
Q9VMX0.1 Q9VMX0

Gene LinkOut

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