U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RpL27A Ribosomal protein L27A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33654, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
RpL27Aprovided by FlyBase
Official Full Name
Ribosomal protein L27Aprovided by FlyBase
Primary source
FLYBASE:FBgn0285948
Locus tag
Dmel_CG15442
See related
AllianceGenome:FB:FBgn0285948
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Posey257; CG15442; Dmel\CG15442; l(2)24EFh; l(2)24Fb; l(2)SH0840; l(2)SH2 0840; L15; M; M(2)24F; M(2)24F-1; M(2)z; M(2)Z; M(2L)z; Mz; M[[z]]; Rp L27A; rpL27a; RpL27a; RpL27a2; RpL27Aa; RpL27Ab
Summary
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Used to study intrinsic cardiomyopathy. Orthologous to human RPL27A (ribosomal protein L27a). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See RpL27A in Genome Data Viewer
Location:
24F3-24F3; 2-12 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4457186..4458364, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4457186..4458364, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene tRNA Selenocysteine associated protein Neighboring gene NADH dehydrogenase (ubiquinone) B8 subunit Neighboring gene GS1-like Neighboring gene ncRNA Neighboring gene mitochondrial ribosomal protein L27 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Protocol for assessing translation in living Drosophila imaginal discs by O-propargyl-puromycin incorporation. Kiparaki M, et al. STAR Protoc, 2023 Dec 15. PMID 37862174, Free PMC Article
  2. The Drosophila melanogaster homolog of ribosomal protein L27a. Garwood J, et al. Biochem Biophys Res Commun, 1994 Jan 28. PMID 8297386
  3. Identification of a cDNA clone encoding DIP1-binding protein in Drosophila melanogaster. De Felice B, et al. Mol Biol Rep, 2004 Sep. PMID 15560371
  4. Localization of minutes to specific polytene chromosome bands by means of overlapping duplications. Broderick DJ, et al. Genetics, 1982 Sep. PMID 7129093, Free PMC Article
  5. Properties and evolutionary potential of newly induced tandem duplications in Drosophila melanogaster. Roberts PA, et al. Genetics, 1982 Sep. PMID 6813191, Free PMC Article

See all (88) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. L27a protein, via interaction with DIP1, could be involved in protein synthesis as well as in cell cycle regulation
    Title: Identification of a cDNA clone encoding DIP1-binding protein in Drosophila melanogaster.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome HDA PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in cytosolic ribosome HDA PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ribosomal protein L27A
Names
CG15442-PA
CG15442-PC
CG15442-PD
RpL27A-PA
RpL27A-PC
RpL27A-PD
lethal (2) SH0840
minute
minute (2) 24F
ribosomal protein L27a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4457186..4458364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001201760.2 → NP_001188689.2  ribosomal protein L27A, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188689.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P41092, Q94530, Q9VR02
    UniProtKB/TrEMBL
    M9MRC9
    Conserved Domains (1) summary
    PTZ00160
    Location:7 → 149
    PTZ00160; 60S ribosomal protein L27a; Provisional

  2. NM_001298672.1 → NP_001285601.1  ribosomal protein L27A, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285601.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P41092, Q94530, Q9VR02
    UniProtKB/TrEMBL
    M9MRC9
    Conserved Domains (1) summary
    PTZ00160
    Location:7 → 149
    PTZ00160; 60S ribosomal protein L27a; Provisional

  3. NM_057615.6 → NP_476963.1  ribosomal protein L27A, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476963.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P41092, Q94530, Q9VR02
    UniProtKB/TrEMBL
    M9MRC9
    Related
    FBpp0077142
    Conserved Domains (1) summary
    PTZ00160
    Location:7 → 149
    PTZ00160; 60S ribosomal protein L27a; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9MRC9 M9MRC9
P41092.2 P41092

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous