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MFS18 Major Facilitator Superfamily Transporter 18 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33650, updated on 4-Jan-2025

Summary

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Official Symbol
MFS18provided by FlyBase
Official Full Name
Major Facilitator Superfamily Transporter 18provided by FlyBase
Primary source
FLYBASE:FBgn0025684
Locus tag
Dmel_CG15438
See related
AllianceGenome:FB:FBgn0025684
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:CK02623; CG15438; CK02623; Dmel\CG15438
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in ATP transport. Is expressed in adult head. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human SLC17A9 (solute carrier family 17 member 9). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See MFS18 in Genome Data Viewer
Location:
24F2-24F3; 2-12 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4446670..4448635, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4446670..4448635, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Seminal fluid protein 24F Neighboring gene uncharacterized protein Neighboring gene modifier of rpr and grim, ubiquitously expressed Neighboring gene Elongator complex protein 3 Neighboring gene uncharacterized protein Neighboring gene tRNA Selenocysteine associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons. Etter PD, et al. BMC Neurosci, 2005 Jun 2. PMID 15932641, Free PMC Article
  2. Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila. Trombley S, et al. Nat Commun, 2023 Oct 14. PMID 37838791, Free PMC Article
  3. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
  4. Drosophila melanogaster as a genetic model system to study neurotransmitter transporters. Martin CA, et al. Neurochem Int, 2014 Jul. PMID 24704795, Free PMC Article
  5. A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. Kopczynski CC, et al. Proc Natl Acad Sci U S A, 1998 Aug 18. PMID 9707585, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ATP transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
major facilitator superfamily transporter 18
Names
CG15438-PA
MFS18-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4446670..4448635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134991.3 → NP_608835.1  major facilitator superfamily transporter 18 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608835.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQZ7
    Related
    FBpp0077146
    Conserved Domains (2) summary
    cd06174
    Location:30 → 432
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:32 → 397
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VQZ7 Q9VQZ7

Gene LinkOut

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