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nsk1 Clp1-interacting, microtubule plus-end binding Nsk1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361470, updated on 18-Sep-2024

Summary

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Official Symbol
nsk1
Official Full Name
Clp1-interacting, microtubule plus-end binding Nsk1
Primary source
PomBase:SPAC3G9.01
Locus tag
SPOM_SPAC3G9.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See nsk1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3181430..3183327, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L23 Neighboring gene ncRNA Neighboring gene 3-oxoacyl-[acyl-carrier-protein] reductase Oar2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation. Chen JS, et al. J Cell Biol, 2011 Nov 14. PMID 22065639, Free PMC Article
  2. Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast. Koch A, et al. Sci Signal, 2011 Jun 28. PMID 21712547
  3. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Buttrick GJ, et al. Mol Biol Cell, 2011 Dec. PMID 21965289, Free PMC Article
  4. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
  5. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nsk1 ensures accurate chromosome segregation by promoting the tethering of kinetochores to spindle poles during anaphase B.
    Title: Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables microtubule plus-end binding EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in attachment of mitotic spindle microtubules to kinetochore IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in centromere clustering at the mitotic interphase nuclear envelope IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Nsk1-Dlc1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in inner plaque of mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle HDA PubMed 
is_active_in mitotic spindle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus HDA PubMed 
is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of outer kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Clp1-interacting, microtubule plus-end binding Nsk1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3181430..3183327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019512.3 → NP_001018258.1  Clp1-interacting, microtubule plus-end binding Nsk1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_001018258.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q7LL22
    Conserved Domains (1) summary
    PTZ00449
    Location:103 → 354
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
Nucleotide Protein
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