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ckk2 calcium/calmodulin-dependent (CaMKK) protein kinase kinase Ckk2/Ppk34 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361146, updated on 18-Sep-2024

Summary

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Official Symbol
ckk2
Official Full Name
calcium/calmodulin-dependent (CaMKK) protein kinase kinase Ckk2/Ppk34
Primary source
PomBase:SPCC1919.01
Locus tag
SPOM_SPCC1919.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ppk34; SPCC830.12
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Genomic context

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See ckk2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003421.2 (2204098..2206069)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleoside-triphosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GPI synthesis protein pig-X Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase AMPK (beta) regulatory subunit Amk2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nitrogen regulates AMPK to control TORC1 signaling. Davie E, et al. Curr Biol, 2015 Feb 16. PMID 25639242, Free PMC Article
  2. Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast. Cisneros-Barroso E, et al. Nucleic Acids Res, 2014 Sep. PMID 25081204, Free PMC Article
  3. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to calcium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of calcineurin-mediated signaling IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
calcium/calmodulin-dependent (CaMKK) protein kinase kinase Ckk2/Ppk34

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2204098..2206069
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023473.4 → NP_588482.2  calcium/calmodulin-dependent (CaMKK) protein kinase kinase Ckk2/Ppk34 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94471, Q9UU87
    Conserved Domains (2) summary
    smart00220
    Location:40 → 331
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14008
    Location:46 → 331
    STKc_LKB1_CaMKK; Catalytic domain of the Serine/Threonine kinases, Liver Kinase B1, Calmodulin Dependent Protein Kinase Kinase, and similar proteins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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