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lcp2a lymphocyte cytosolic protein 2a [ Danio rerio (zebrafish) ]

Gene ID: 336073, updated on 9-Dec-2024

Summary

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Official Symbol
lcp2aprovided by ZNC
Official Full Name
lymphocyte cytosolic protein 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-97
See related
Ensembl:ENSDARG00000055955 AllianceGenome:ZFIN:ZDB-GENE-041114-97
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fj47a12; zgc:101809
Summary
Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway and intracellular signal transduction. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human LCP2 (lymphocyte cytosolic protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See lcp2a in Genome Data Viewer
Location:
chromosome: 21
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (30306356..30347612)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (30269583..30310917)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene stem-loop binding protein 2 Neighboring gene zinc finger, matrin-type 2 Neighboring gene forkhead box I3a Neighboring gene uncharacterized LOC137488827

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo. Jerison ER, et al. Elife, 2020 May 19. PMID 32427565, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC101809

General protein information

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Preferred Names
lymphocyte cytosolic protein 2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214717.1 → NP_999882.1  lymphocyte cytosolic protein 2a

    See identical proteins and their annotated locations for NP_999882.1

    Status: PROVISIONAL

    Source sequence(s)
    AF388204
    UniProtKB/TrEMBL
    Q8JI36
    Conserved Domains (2) summary
    cd09522
    Location:10 → 78
    SAM_SLP76; SAM domain of SLP76 subfamily
    cl15255
    Location:380 → 500
    SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    30306356..30347612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005161289.5 → XP_005161346.1  lymphocyte cytosolic protein 2a isoform X1

    UniProtKB/TrEMBL
    A0A8M2B875
    Conserved Domains (2) summary
    cd09522
    Location:10 → 78
    SAM_SLP76; SAM domain of SLP76 subfamily
    cl15255
    Location:389 → 509
    SH2; Src homology 2 (SH2) domain

  2. XM_005161291.5 → XP_005161348.1  lymphocyte cytosolic protein 2a isoform X2

    UniProtKB/TrEMBL
    A0A8M2B8A4
    Related
    ENSDARP00000059419.7, ENSDART00000059420.7
    Conserved Domains (2) summary
    cd09522
    Location:10 → 78
    SAM_SLP76; SAM domain of SLP76 subfamily
    cl15255
    Location:381 → 501
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein Strain
Heading Accession and Version

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