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ND-AGGG NADH dehydrogenase (ubiquinone) AGGG subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3355155, updated on 9-Dec-2024

Summary

Official Symbol
ND-AGGGprovided by FlyBase
Official Full Name
NADH dehydrogenase (ubiquinone) AGGG subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0058002
Locus tag
Dmel_CG40002
See related
AllianceGenome:FB:FBgn0058002
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG40002; Dmel\CG40002; dNDUFB2A; l7A; NDUFB2
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Part of respiratory chain complex I. Is expressed in adult head and adult heart. Orthologous to human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ND-AGGG in Genome Data Viewer
Location:
80F9-80F9; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (24976254..24977118)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3LHet NW_001848857.1 (459586..460450)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46483 Neighboring gene SET domain containing 1 Neighboring gene Mediator complex subunit 21 Neighboring gene Ubiquinol-cytochrome c reductase 11 kDa subunit

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IC
Inferred by Curator
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of respiratory chain complex I IDA
Inferred from Direct Assay
more info
PubMed 
part_of respiratory chain complex I IEA
Inferred from Electronic Annotation
more info
 
part_of respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
NADH dehydrogenase (ubiquinone) AGGG subunit
Names
CG40002-PA
CG40002-PB
NADH ubiquinone oxidoreductase AGGG
NADH:ubiquinone oxidoreductase AGGG subunit
ND-AGGG-PA
ND-AGGG-PB
lethal 7A
lethal7A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    24976254..24977118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001015476.3NP_001015476.1  NADH dehydrogenase (ubiquinone) AGGG subunit, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015476.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7PL91
    Conserved Domains (1) summary
    pfam14813
    Location:2693
    NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2
  2. NM_001300709.1NP_001287638.1  NADH dehydrogenase (ubiquinone) AGGG subunit, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287638.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7PL91
    Conserved Domains (1) summary
    pfam14813
    Location:2693
    NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2