Tim17b Translocase of the inner mitochondrial membrane 17b [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Tim17bprovided by FlyBase
Official Full Name: Translocase of the inner mitochondrial membrane 17bprovided by FlyBase
Primary source: FLYBASE:FBgn0263977
Locus tag: Dmel_CG40451
See related: AllianceGenome:FB:FBgn0263977
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG40451; Dmel\CG40451
Summary: Contributes to protein transmembrane transporter activity. Involved in protein import into mitochondrial matrix and protein insertion into mitochondrial inner membrane. Located in mitochondrial inner membrane. Is expressed in adult head; adult heart; and organism. Orthologous to human TIMM17A (translocase of inner mitochondrial membrane 17A) and TIMM17B (translocase of inner mitochondrial membrane 17B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (3734855..3745306)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3RHet	NW_001848858.1 (1813575..1824026, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
contributes_to protein transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to protein transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into mitochondrial matrix	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein insertion into mitochondrial inner membrane	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of TIM23 mitochondrial import inner membrane translocase complex	TAS Traceable Author Statement more info	PubMed
located_in mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed

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