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MFS17 Major Facilitator Superfamily Transporter 17 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3354861, updated on 4-Jan-2025

Summary

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Official Symbol
MFS17provided by FlyBase
Official Full Name
Major Facilitator Superfamily Transporter 17provided by FlyBase
Primary source
FLYBASE:FBgn0058263
Locus tag
Dmel_CG40263
See related
AllianceGenome:FB:FBgn0058263
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD07241; bs24e02.y1; CG40263; Dmel\CG40263
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See MFS17 in Genome Data Viewer
Location:
41A1-41A1; 2-55 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (2494742..2565385, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2RHet NW_001848856.1 (1265405..1336048, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46487 Neighboring gene pseudo Neighboring gene mir-2279 stem loop Neighboring gene long non-coding RNA:CR46481 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HP1a targets the Drosophila KDM4A demethylase to a subset of heterochromatic genes to regulate H3K36me3 levels. Lin CH, et al. PLoS One, 2012. PMID 22761891, Free PMC Article
  2. Genome ARTIST_v2-An Autonomous Bioinformatics Tool for Annotation of Natural Transposons in Sequenced Genomes. Ecovoiu AA, et al. Int J Mol Sci, 2022 Oct 21. PMID 36293549, Free PMC Article
  3. Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins. Kramer MC, et al. Genes Dev, 2015 Oct 15. PMID 26450910, Free PMC Article
  4. Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Roignant JY, et al. Cell, 2010 Oct 15. PMID 20946982, Free PMC Article
  5. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org
  • mir-2279-RA; Dmel\mir-2279-RA; CR42911-RA; Dmel\CR42911-RA
  • mir-2279-RB; Dmel\mir-2279-RB; CR42911-RB; Dmel\CR42911-RB

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
major facilitator superfamily transporter 17
Names
CG40263-PF
CG40263-PG
CG40263-PH
CG40263-PI
CG40263-PJ
MFS17-PF
MFS17-PG
MFS17-PH
MFS17-PI
MFS17-PJ

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    2494742..2565385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001110894.2 → NP_001104364.2  major facilitator superfamily transporter 17, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001104364.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0C4DHN3

  2. NM_001015096.4 → NP_001015096.2  major facilitator superfamily transporter 17, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015096.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8Y4X9, Q494G7, Q8IH77
    Conserved Domains (2) summary
    cd06174
    Location:41 → 467
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:34 → 477
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

  3. NM_001276229.1 → NP_001263158.1  major facilitator superfamily transporter 17, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263158.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0C4DHN7, Q8IH77
    Conserved Domains (1) summary
    cd06174
    Location:41 → 438
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

  4. NM_001110895.3 → NP_001104365.2  major facilitator superfamily transporter 17, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001104365.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8Y4X9, Q494G7, Q8IH77
    Conserved Domains (2) summary
    cd06174
    Location:41 → 467
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:34 → 477
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

  5. NM_001015095.4 → NP_001015095.1  major facilitator superfamily transporter 17, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015095.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7PLD0, Q8IH77
    Conserved Domains (2) summary
    cd06174
    Location:41 → 438
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:34 → 443
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0C4DHN3 A0A0C4DHN3
A0A0C4DHN7 A0A0C4DHN7
Q494G7 Q494G7
Q7PLD0 Q7PLD0
Q8IH77 Q8IH77

Gene LinkOut

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