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Fign - Fidgetin

Enables microtubule severing ATPase activity. Involved in several processes, including microtubule severing; mitotic sister chromatid segregation; and regulation of microtubule depolymerization. Located in centrosome and chromosome. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to several human genes including FIGNL1 (fidgetin like 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa