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scaf6 SR-related CTD associated factor 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3346235, updated on 2-Nov-2024

Summary

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Official Symbol
scaf6provided by FlyBase
Official Full Name
SR-related CTD associated factor 6provided by FlyBase
Primary source
FLYBASE:FBgn0261872
Locus tag
Dmel_CG33522
See related
AllianceGenome:FB:FBgn0261872
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BP1040; BP1047; CG14058; CG32168; CG33522; CG6615; CG6626; Dmel\CG33522
Summary
Predicted to enable RNA binding activity. Predicted to be involved in intracellular calcium ion homeostasis. Predicted to be active in perinuclear region of cytoplasm. Is expressed in several structures, including central brain primordium; ganglia; larval nervous system; and ventral nerve cord primordium. Orthologous to human CHERP (calcium homeostasis endoplasmic reticulum protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See scaf6 in Genome Data Viewer
Location:
73E5-73E5; 3-45 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17036859..17042574, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17029959..17035674, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45756 Neighboring gene Insulin-like peptide 8 Neighboring gene long non-coding RNA:CR43250 Neighboring gene bad egg Neighboring gene PAPS transporter 2 Neighboring gene POP5 ribonuclease P/MRP subunit Neighboring gene Troponin C at 73F

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in Drosophila. Hayashi R, et al. G3 (Bethesda), 2014 Apr 16. PMID 24531791, Free PMC Article
  2. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
  3. The Drosophila melanogaster Genetic Reference Panel. Mackay TF, et al. Nature, 2012 Feb 8. PMID 22318601, Free PMC Article
  4. A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Yandell M, et al. Proc Natl Acad Sci U S A, 2005 Feb 1. PMID 15668397, Free PMC Article
  5. Identification of proteasome components required for apical localization of Chaoptin using functional genomics. Yano H, et al. J Neurogenet, 2012 Mar. PMID 22417167

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SR-related CTD associated factor 6
Names
BP1047
CG33522-PA
CG33522-PC
CG33522-PE
scaf6-PA
scaf6-PC
scaf6-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17036859..17042574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038939.2 → NP_001034028.2  SR-related CTD associated factor 6, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001034028.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A023GQ04
    Conserved Domains (1) summary
    pfam01805
    Location:13 → 61
    Surp; Surp module

  2. NM_001014589.4 → NP_001014589.1  SR-related CTD associated factor 6, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014589.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E33, Q8I9J8
    Conserved Domains (3) summary
    pfam01585
    Location:885 → 933
    G-patch; G-patch domain
    pfam01805
    Location:13 → 61
    Surp; Surp module
    pfam04818
    Location:271 → 329
    CTD_bind; RNA polymerase II-binding domain

  3. NM_001169986.3 → NP_001163457.1  SR-related CTD associated factor 6, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163457.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86MQ9
    Conserved Domains (1) summary
    pfam01805
    Location:13 → 61
    Surp; Surp module
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A023GQ04 A0A023GQ04
Q59E33 Q59E33
Q7K2G6 Q7K2G6
Q86MQ9 Q86MQ9
Q8I9J8 Q8I9J8

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