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c1qbp complement component 1, q subcomponent binding protein [ Danio rerio (zebrafish) ]

Gene ID: 334619, updated on 4-Jan-2025

Summary

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Official Symbol
c1qbpprovided by ZNC
Official Full Name
complement component 1, q subcomponent binding proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-408
See related
Ensembl:ENSDARG00000039887 AllianceGenome:ZFIN:ZDB-GENE-050417-408
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa14h03; sb:cb785; wu:fa14h03; zgc:110137; si:ch1073-329n19.2
Summary
Predicted to be involved in cytosolic ribosome assembly. Predicted to act upstream of or within adaptive immune response. Predicted to be located in mitochondrial matrix. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; musculature system; and segmental plate. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 33. Orthologous to human C1QBP (complement C1q binding protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See c1qbp in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (3914402..3927763, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (3590949..3604310, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene MLX interacting protein like Neighboring gene RPA interacting protein Neighboring gene zinc finger, HIT-type containing 3 Neighboring gene myosin XIX Neighboring gene unconventional myosin-XIX-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Mother-Specific Signature in the Maternal Transcriptome Composition of Mature, Unfertilized Zebrafish Eggs. Rauwerda H, et al. PLoS One, 2016. PMID 26799215, Free PMC Article
  2. Essential role of an ERV-derived Env38 protein in adaptive humoral immunity against an exogenous SVCV infection in a zebrafish model. Hong Y, et al. PLoS Pathog, 2023 Apr. PMID 37014912, Free PMC Article
  3. Amino acid primed mTOR activity is essential for heart regeneration. Miklas JW, et al. iScience, 2022 Jan 21. PMID 34988408, Free PMC Article
  4. Proteomic analysis of anatoxin-a acute toxicity in zebrafish reveals gender specific responses and additional mechanisms of cell stress. Carneiro M, et al. Ecotoxicol Environ Saf, 2015 Oct. PMID 26046835
  5. Deconvoluting Wavelengths Leading to Fluorescent Light Induced Inflammation and Cellular Stress in Zebrafish (Danio rerio). Boswell M, et al. Sci Rep, 2020 Feb 24. PMID 32094353, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC110137, MGC191630

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
  
involved_in cytosolic ribosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
complement component 1 Q subcomponent-binding protein, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017858.2 → NP_001017858.2  complement component 1 Q subcomponent-binding protein, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    EH440105, EH466913, EH483432
    UniProtKB/TrEMBL
    A0A8M1N5K7, F1R3F7
    Related
    ENSDARP00000058345.5, ENSDART00000058346.7
    Conserved Domains (1) summary
    pfam02330
    Location:79 → 261
    MAM33; Mitochondrial glycoprotein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    3914402..3927763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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