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baz1a bromodomain adjacent to zinc finger domain, 1A [ Danio rerio (zebrafish) ]

Gene ID: 334173, updated on 4-Jan-2025

Summary

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Official Symbol
baz1aprovided by ZNC
Official Full Name
bromodomain adjacent to zinc finger domain, 1Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6105
See related
Ensembl:ENSDARG00000099745 AllianceGenome:ZFIN:ZDB-GENE-030131-6105
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fi34e04; im:6907928; wu:fi34e04
Summary
Predicted to enable metal ion binding activity. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in nucleus. Orthologous to human BAZ1A (bromodomain adjacent to zinc finger domain 1A). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See baz1a in Genome Data Viewer
Location:
chromosome: 17
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (10031791..10060007, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (9875751..9903970, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 6 Neighboring gene cofilin 2 (muscle) Neighboring gene zgc:109986 Neighboring gene signal recognition particle 54

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  2. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
bromodomain adjacent to zinc finger domain protein 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365143.1 → NP_001352072.1  bromodomain adjacent to zinc finger domain protein 1A isoform 1

    Status: VALIDATED

    Source sequence(s)
    BX088587, CABZ01005612, CABZ01042488, CU928207
    UniProtKB/TrEMBL
    A0A8N7TEI0
    Conserved Domains (7) summary
    smart00571
    Location:406 → 467
    DDT; domain in different transcription and chromosome remodeling factors
    cd15627
    Location:1118 → 1163
    PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
    pfam10537
    Location:23 → 122
    WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
    pfam15612
    Location:570 → 615
    WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
    pfam15613
    Location:759 → 875
    WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    cl02556
    Location:1353 → 1457
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    cl26511
    Location:618 → 747
    Neuromodulin_N; Gap junction protein N-terminal region

  2. NM_001365144.1 → NP_001352073.1  bromodomain adjacent to zinc finger domain protein 1A isoform 2

    Status: VALIDATED

    Source sequence(s)
    BX088587, CABZ01005612, CABZ01042488, CU928207
    UniProtKB/TrEMBL
    A0A8M6YTY8
    Related
    ENSDARP00000086641.5, ENSDART00000092209.6
    Conserved Domains (7) summary
    smart00571
    Location:406 → 467
    DDT; domain in different transcription and chromosome remodeling factors
    cd15627
    Location:1118 → 1163
    PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
    pfam10537
    Location:23 → 122
    WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
    pfam15612
    Location:570 → 615
    WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
    pfam15613
    Location:759 → 875
    WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
    cl02556
    Location:1352 → 1456
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
    cl26511
    Location:618 → 747
    Neuromodulin_N; Gap junction protein N-terminal region

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    10031791..10060007 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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