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naa15b N-alpha-acetyltransferase 15, NatA auxiliary subunit b [ Danio rerio (zebrafish) ]

Gene ID: 334099, updated on 9-Dec-2024

Summary

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Official Symbol
naa15bprovided by ZNC
Official Full Name
N-alpha-acetyltransferase 15, NatA auxiliary subunit bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6031
See related
Ensembl:ENSDARG00000030368 AllianceGenome:ZFIN:ZDB-GENE-030131-6031
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
narg1b; fi31d06; wu:fi31d06
Summary
Predicted to enable acetyltransferase activator activity. Acts upstream of or within myotome development. Predicted to be part of NatA complex. Predicted to be active in cytoplasm. Is expressed in eye; immature eye; midbrain; optic tectum; and somite. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 50. Orthologous to human NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See naa15b in Genome Data Viewer
Location:
chromosome: 1
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (40613297..40641474)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39895224..39923401)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene short coiled-coil protein a Neighboring gene calmegin Neighboring gene uncharacterized LOC137493459 Neighboring gene ras-related protein Rab-33B Neighboring gene wu:fc34e06

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Naa15 knockdown enhances c2c12 myoblast fusion and induces defects in zebrafish myotome morphogenesis. Monestier O, et al. Comp Biochem Physiol B Biochem Mol Biol, 2019 Feb. PMID 30502388
  2. Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses. Lui EY, et al. J Genet Genomics, 2016 Aug 20. PMID 27503704
  3. Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain. Huang L, et al. Sci Rep, 2019 Feb 12. PMID 30755680, Free PMC Article
  4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acetyltransferase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within myotome development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of NatA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
N-alpha-acetyltransferase 15, NatA auxiliary subunit b
Names
NMDA receptor-regulated gene 1b
transcriptional coactivator tubedown-100

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203321.2 → NP_976066.2  N-alpha-acetyltransferase 15, NatA auxiliary subunit b

    Status: VALIDATED

    Source sequence(s)
    BX511216, CU856624, FO904879
    UniProtKB/TrEMBL
    A0A0R4I9S5, A0A8M1PEL4
    Related
    ENSDARP00000130499.2, ENSDART00000168067.2
    Conserved Domains (3) summary
    sd00006
    Location:82 → 108
    TPR; TPR repeat [structural motif]
    pfam12569
    Location:187 → 698
    NARP1; NMDA receptor-regulated protein 1
    pfam13414
    Location:82 → 145
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    40613297..40641474
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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