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rnf168 - ring finger protein 168

Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; nucleosome binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including DNA metabolic process; DNA repair-dependent chromatin remodeling; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within DNA repair and chromatin organization. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus and site of double-strand break. Human ortholog(s) of this gene implicated in RIDDLE syndrome. Orthologous to human RNF168 (ring finger protein 168). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa