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AIF - Apoptosis inducing factor

Predicted to enable DNA binding activity; FAD binding activity; and NAD(P)H oxidase H2O2-forming activity. Involved in defense response to fungus; mitochondrial ATP synthesis coupled electron transport; and programmed cell death involved in cell development. Located in mitochondrial intermembrane space. Is expressed in adult head; adult heart; organism; and spermatozoon. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked recessive 4; X-linked deafness 5; and combined oxidative phosphorylation deficiency 6. Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to AIF

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Species Gene Architecture aa