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mRpL48 mitochondrial ribosomal protein L48 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33348, updated on 9-Dec-2024

Summary

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Official Symbol
mRpL48provided by FlyBase
Official Full Name
mitochondrial ribosomal protein L48provided by FlyBase
Primary source
FLYBASE:FBgn0031357
Locus tag
Dmel_CG17642
See related
AllianceGenome:FB:FBgn0031357
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17642; Dmel\CG17642; MRP-L48
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrial ribosome. Is expressed in several structures, including dorsal pharyngeal muscle primordium; embryonic/larval midgut; larval muscle cell; larval muscle system; and mesoderm. Orthologous to human MRPL48 (mitochondrial ribosomal protein L48). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See mRpL48 in Genome Data Viewer
Location:
22B1-22B1; 2-3 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1710462..1711465)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1710462..1711465)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene capping protein beta Neighboring gene antisense RNA:CR44976 Neighboring gene uncharacterized protein Neighboring gene fritz Neighboring gene Replication in mitochondria 2 Neighboring gene Enolase Neighboring gene Ribosomal RNA processing 40

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The WD40 repeat protein fritz links cytoskeletal planar polarity to frizzled subcellular localization in the Drosophila epidermis. Collier S, et al. Genetics, 2005 Apr. PMID 15654087, Free PMC Article
  2. Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts. Januschke J, et al. Nat Cell Biol, 2013 Mar. PMID 23354166
  3. Retrotransposon-gene associations are widespread among D. melanogaster populations. Franchini LF, et al. Mol Biol Evol, 2004 Jul. PMID 15014149
  4. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Garelli A, et al. Science, 2012 May 4. PMID 22556250
  5. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
is_active_in mitochondrial ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial ribosomal protein L48
Names
CG17642-PA
CG17642-PB
mRpL48-PA
mRpL48-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    1710462..1711465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134769.3 → NP_608613.1  mitochondrial ribosomal protein L48, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608613.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQ35
    Related
    FBpp0077550
    Conserved Domains (1) summary
    pfam00338
    Location:50 → 144
    Ribosomal_S10; Ribosomal protein S10p/S20e

  2. NM_001272949.1 → NP_001259878.1  mitochondrial ribosomal protein L48, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259878.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQ35
    Conserved Domains (1) summary
    pfam00338
    Location:50 → 144
    Ribosomal_S10; Ribosomal protein S10p/S20e
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VQ35 Q9VQ35

Gene LinkOut

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