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RpLP1 Ribosomal protein LP1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33214, updated on 9-Dec-2024

Summary

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Official Symbol
RpLP1provided by FlyBase
Official Full Name
Ribosomal protein LP1provided by FlyBase
Primary source
FLYBASE:FBgn0002593
Locus tag
Dmel_CG4087
See related
AllianceGenome:FB:FBgn0002593
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4087; chr2L:420593..420726; Dmel\CG4087; LP1; M(2)21C; M(2)21C1-2; P1; RLA1_DROME; rp21C; RP21C; rpa2; rpA2; RpA2; RPA2; Rplp1; RpLp1; rpP2; RpP2
Summary
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Used to study intrinsic cardiomyopathy. Orthologous to human RPLP1 (ribosomal protein lateral stalk subunit P1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See RpLP1 in Genome Data Viewer
Location:
21C2-21C2; 2-0.7 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (419952..420864)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (419952..420864)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Adaptor Protein complex 2, alpha subunit Neighboring gene ebi Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cDNA and deduced amino acid sequence of Drosophila rp21C, another 'A'-type ribosomal protein. Wigboldus JD. Nucleic Acids Res, 1987 Dec 10. PMID 3122177, Free PMC Article
  2. Drosophila acidic ribosomal protein rpA2: sequence and characterization. Olson PF, et al. J Cell Biochem, 1993 Mar. PMID 8501137
  3. A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes. Baumann DG, et al. Nucleic Acids Res, 2017 Oct 13. PMID 28977400, Free PMC Article
  4. GFZF, a Glutathione S-Transferase Protein Implicated in Cell Cycle Regulation and Hybrid Inviability, Is a Transcriptional Coactivator. Baumann DG, et al. Mol Cell Biol, 2018 Feb 15. PMID 29158293, Free PMC Article
  5. The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery. Parry TJ, et al. Genes Dev, 2010 Sep 15. PMID 20801935, Free PMC Article

See all (79) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribonucleoprotein complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome HDA PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in cytosolic ribosome HDA PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal protein LP1
Names
ACIDIC RIBOSOMAL PROTEIN LP1
CG4087-PA
CG4087-PB
Minute(2)21C
Ribosomal-protein-A2
RpLP1-PA
RpLP1-PB
ribosomal protein A2
ribosomal protein P2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    419952..420864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272893.1 → NP_001259822.1  ribosomal protein LP1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259822.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08570, Q9VPP6
    UniProtKB/TrEMBL
    M9PBK5
    Conserved Domains (1) summary
    cd05831
    Location:6 → 111
    Ribosomal_P1; Ribosomal protein P1. This subfamily represents the eukaryotic large ribosomal protein P1. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P1 is located in the L12 stalk, with proteins ...

  2. NM_057282.4 → NP_476630.1  ribosomal protein LP1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476630.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08570, Q9VPP6
    UniProtKB/TrEMBL
    M9PBK5
    Related
    FBpp0077716
    Conserved Domains (1) summary
    cd05831
    Location:6 → 111
    Ribosomal_P1; Ribosomal protein P1. This subfamily represents the eukaryotic large ribosomal protein P1. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P1 is located in the L12 stalk, with proteins ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PBK5 M9PBK5
P08570.2 P08570

Gene LinkOut

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