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Polr1B - RNA polymerase I subunit B

Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and ribonucleoside binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in transcription by RNA polymerase I. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; gut section; and mesoderm. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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Species Gene Architecture aa