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Pi3K21B - Pi3K21B

Enables kinase binding activity and phosphotyrosine residue binding activity. Involved in several processes, including insulin receptor signaling pathway; negative regulation of feeding behavior; and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Part of phosphatidylinositol 3-kinase complex, class IA. Is expressed in several structures, including anterior-posterior subdivision of organism; embryonic/larval midgut; embryonic/larval midgut primordium; germline cell; and pole plasm. Human ortholog(s) of this gene implicated in several diseases, including SHORT syndrome; agammaglobulinemia 7; carcinoma (multiple); endometrial cancer (multiple); and immunodeficiency 36. Orthologous to several human genes including PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Pi3K21B

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Species Gene Architecture aa