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Cda5 Chitin deacetylase-like 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33158, updated on 4-Jan-2025

Summary

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Official Symbol
Cda5provided by FlyBase
Official Full Name
Chitin deacetylase-like 5provided by FlyBase
Primary source
FLYBASE:FBgn0051973
Locus tag
Dmel_CG31973
See related
AllianceGenome:FB:FBgn0051973
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH43162; CG2761; CG2776; CG31973; DmCDA5; Dmel\CG31973
Summary
Predicted to enable chitin deacetylase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in extracellular region. Is expressed in several structures, including embryonic epipharynx; embryonic head epidermis; embryonic hypopharynx; epidermis; and gut section. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Cda5 in Genome Data Viewer
Location:
21B1-21B1; 2-0.5 cM
Exon count:
18
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (25402..65404, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (25402..65404, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lethal (2) giant larvae Neighboring gene antisense RNA:CR43609 Neighboring gene Ionotropic receptor 21a Neighboring gene long non-coding RNA:CR46254 Neighboring gene long non-coding RNA:CR45339 Neighboring gene long non-coding RNA:CR45340 Neighboring gene debra

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects. Dixit R, et al. Insect Biochem Mol Biol, 2008 Apr. PMID 18342249
  2. The Ionotropic Receptors IR21a and IR25a mediate cool sensing in Drosophila. Ni L, et al. Elife, 2016 Apr 29. PMID 27126188, Free PMC Article
  3. Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. Grzeschik NA, et al. Dev Biol, 2007 Nov 1. PMID 17870065, Free PMC Article
  4. Context-dependent impact of the dietary non-essential amino acid tyrosine on Drosophila physiology and longevity. Kosakamoto H, et al. Sci Adv, 2024 Aug 30. PMID 39213345, Free PMC Article
  5. Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures. Sytnikova YA, et al. Genome Res, 2014 Dec. PMID 25267525, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c27788-27530 mobile_element_type = transposon:INE-1{}1753

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
enables chitin deacetylase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chitin deacetylase-like 5
Names
CG31973-PA
CG31973-PB
CG31973-PE
CG31973-PF
CG31973-PG
CG31973-PH
CG31973-PI
CG31973-PJ
Cda5-PA
Cda5-PB
Cda5-PE
Cda5-PF
Cda5-PG
Cda5-PH
Cda5-PI
Cda5-PJ
NP_001097044.2
NP_001097045.1
NP_001245805.1
NP_001245806.1
NP_001245807.1
NP_001245808.1
NP_722589.1
NP_722590.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    25402..65404 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258877.2 → NP_001245806.1  chitin deacetylase-like 5, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245806.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NCL3
    Conserved Domains (2) summary
    cd10975
    Location:1456 → 1718
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  2. NM_001103575.2 → NP_001097045.1  chitin deacetylase-like 5, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097045.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8V4
    Conserved Domains (2) summary
    cd10975
    Location:705 → 968
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  3. NM_164353.2 → NP_722589.1  chitin deacetylase-like 5, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722589.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPI4
    Related
    FBpp0077821
    Conserved Domains (2) summary
    cd10975
    Location:705 → 967
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  4. NM_164354.3 → NP_722590.2  chitin deacetylase-like 5, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722590.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPI3
    Conserved Domains (2) summary
    cd10975
    Location:1664 → 1926
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  5. NM_001258878.2 → NP_001245807.1  chitin deacetylase-like 5, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245807.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NE36
    Conserved Domains (2) summary
    cd10975
    Location:557 → 819
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  6. NM_001103574.3 → NP_001097044.2  chitin deacetylase-like 5, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097044.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8DYS5
    Conserved Domains (2) summary
    cd10975
    Location:1556 → 1818
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  7. NM_001258879.2 → NP_001245808.1  chitin deacetylase-like 5, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245808.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NCX5
    Conserved Domains (2) summary
    cd10975
    Location:1516 → 1778
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain

  8. NM_001258876.2 → NP_001245805.1  chitin deacetylase-like 5, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245805.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NEJ4
    Conserved Domains (2) summary
    cd10975
    Location:1228 → 1490
    CE4_CDA_like_2; Putative catalytic domain of chitin deacetylase-like proteins
    pfam01607
    Location:58 → 106
    CBM_14; Chitin binding Peritrophin-A domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8DYS5 A8DYS5
M9NCL3 M9NCL3
M9NCX5 M9NCX5
M9NE36 M9NE36
M9NEJ4 M9NEJ4
Q0E8V4 Q0E8V4
Q8MQI4 Q8MQI4
Q9VPI3 Q9VPI3
Q9VPI4 Q9VPI4

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