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mst misato [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33119, updated on 9-Dec-2024

Summary

Official Symbol
mstprovided by FlyBase
Official Full Name
misatoprovided by FlyBase
Primary source
FLYBASE:FBgn0020272
Locus tag
Dmel_CG1424
See related
AllianceGenome:FB:FBgn0020272
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1424; Dmel\CG1424; l(1)19Fg; l(1)LB14; l(1)LB20; LB-20; LB20; lLB14; MST1/2
Summary
Involved in mitotic spindle assembly. Located in cytoplasm. Is expressed in adult brain; brain; embryonic/larval fat body; imaginal disc; and ovary. Used to study myotonia congenita. Orthologous to human MSTO1 (misato mitochondrial distribution and morphology regulator 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See mst in Genome Data Viewer
Location:
20A1-20A1; 1-66 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21388977..21391533)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21260004..21262560)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45611 Neighboring gene sluggish A Neighboring gene ncRNA Neighboring gene DEAD-box helicase 56 Neighboring gene long non-coding RNA:CR45500 Neighboring gene la costa

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic sister chromatid segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic spindle assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
misato
Names
CG1424-PA
CG1424-PB
MST1/2
lethal(1)19Fg
mst-PA
mst-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    21388977..21391533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298589.1NP_001285518.1  misato, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285518.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O01939, Q8MSB2
    UniProtKB/TrEMBL
    X2JG23
    Conserved Domains (1) summary
    cd06060
    Location:5570
    misato; Misato segment II tubulin-like domain
  2. NM_078711.5NP_523435.1  misato, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523435.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O01939, Q8MSB2
    UniProtKB/TrEMBL
    X2JG23
    Related
    FBpp0076907
    Conserved Domains (1) summary
    cd06060
    Location:5570
    misato; Misato segment II tubulin-like domain