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CG1486 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33108, updated on 4-Jan-2025

Summary

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Official Symbol
CG1486provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031174
Locus tag
Dmel_CG1486
See related
AllianceGenome:FB:FBgn0031174
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1486
Summary
Predicted to enable carbon-carbon lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in carboxylic acid metabolic process. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic proventriculus; embryonic ventral epidermis; and gland. Orthologous to several human genes including PDXDC1 (pyridoxal dependent decarboxylase domain containing 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG1486 in Genome Data Viewer
Location:
19F4-19F4; 1-65 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21324046..21328150)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21195073..21199177)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene SRA stem-loop interacting RNA binding protein 1 Neighboring gene anorexia Neighboring gene Dullard Neighboring gene tweety Neighboring gene flightless I

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. Liu Z, et al. Dev Growth Differ, 2011 Aug. PMID 21790556
  2. The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription. Zouaz A, et al. EMBO J, 2017 Oct 2. PMID 28871058, Free PMC Article
  3. Phenotypic plasticity and genotype by environment interaction for olfactory behavior in Drosophila melanogaster. Sambandan D, et al. Genetics, 2008 Jun. PMID 18505870, Free PMC Article
  4. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
  5. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbon-carbon lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1486-PA
CG1486-PB
NP_608450.1
NP_728413.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    21324046..21328150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134606.4 → NP_608450.1  uncharacterized protein Dmel_CG1486, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608450.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRG8
    Related
    FBpp0076891
    Conserved Domains (2) summary
    cl18945
    Location:159 → 384
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    cl23807
    Location:725 → 801
    WWbp; WW-domain ligand protein

  2. NM_167743.2 → NP_728413.1  uncharacterized protein Dmel_CG1486, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728413.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VRG8
    Related
    FBpp0076892
    Conserved Domains (2) summary
    cl18945
    Location:159 → 384
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    cl23807
    Location:725 → 801
    WWbp; WW-domain ligand protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VRG8 Q9VRG8

Gene LinkOut

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