Syx16 Syntaxin 16 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Syx16provided by FlyBase
Official Full Name: Syntaxin 16provided by FlyBase
Primary source: FLYBASE:FBgn0031106
Locus tag: Dmel_CG1467
See related: AllianceGenome:FB:FBgn0031106
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG1467; Dm Syx16; Dmel\CG1467; DmSyx16; dStx16; dSyx 16; dSyx16; Syx; SYX16
Summary: Enables SNAP receptor activity. Involved in Golgi vesicle transport. Located in Golgi trans cisterna; lysosome; and membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in pseudohypoparathyroidism type IB. Orthologous to human STX16 (syntaxin 16). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (20392334..20393751, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (20263361..20264778, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

syntaxin 16 may selectively regulate Golgi dynamics
Title: Drosophila syntaxin 16 is a Q-SNARE implicated in Golgi dynamics.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables SNAP receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables SNAP receptor activity	IEA Inferred from Electronic Annotation more info
enables SNAP receptor activity	IPI Inferred from Physical Interaction more info	PubMed
enables SNAP receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables SNAP receptor activity	NAS Non-traceable Author Statement more info	PubMed
enables SNARE binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi vesicle transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in neurotransmitter secretion	NAS Non-traceable Author Statement more info	PubMed
involved_in synaptic vesicle docking	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	IC Inferred by Curator more info	PubMed
located_in Golgi trans cisterna	IDA Inferred from Direct Assay more info	PubMed
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SNARE complex	IC Inferred by Curator more info	PubMed
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosome	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in plasma membrane	NAS Non-traceable Author Statement more info	PubMed