Zw - Zwischenferment
Enables glucose-6-phosphate dehydrogenase activity. Involved in pentose-phosphate shunt, oxidative branch. Predicted to be active in cytosol. Is expressed in adult fat body and adult head. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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